The DEEP-DV consortium, led by Prof. Dr. Nicole Fischer and Prof. Dr. Melanie Brinkmann, has been awarded the 2026 North German Science Award in recognition of its research achievements within a cross-state collaboration. With this award, the five northern German federal states of Bremen, Hamburg, Mecklenburg-Western Pomerania, Lower Saxony and Schleswig-Holstein honour outstanding collaborations in the field of infectious disease research.
“Chronic viral infections and their long-term consequences are becoming increasingly important in an ageing society and for vulnerable groups. By combining scientific expertise and state-of-the-art technologies, we aim to gain a better understanding of persistent viral infections and develop new approaches to prevention and therapy,” says Prof. Dr. Nicole Fischer (Hamburg site).
One of the consortium’s key projects is the development of the DEEP-DV Transcription Atlas, a molecular map of DNA virus infections that will be made available to the international research community.
“DEEP-DV demonstrates what can be achieved when universities and non-university research institutions combine their complementary strengths. The award therefore recognizes not only the project’s scientific achievements, but also the close collaboration and strong research structures that we have jointly established in northern Germany,” says Prof. Dr. Melanie Brinkmann (Braunschweig site).
FOR5200 DEEP-DV
Disrupt - Evade - Exploit
Gene expression and host response programming in DNA virus infection
Our Mission
The DFG-funded Research Unit FOR5200 DEEP-DV unites experts in molecular biology, virology, and bioinformatics to uncover how nuclear DNA viruses disrupt, evade or exploit host gene expression networks to pave the way for lytic, abortive, or persistent infection. Using state-of-the-art experimental and bioinformatic approaches, we compare virus–host interactions across major DNA virus families, including herpesviruses, adenoviruses, and polyomaviruses.



The single-cell DEEP-DV Transcription Atlas (Z01) captures viral and host gene expression over time during lytic infection.
Z1
Caroline Friedel &
Florian Erhard
By applying standardized protocols as well as bioinformatic analysis across all projects, the DEEP-DV Atlas enables direct comparisons between viruses.

P07
Thomas Stamminger

P08
Sabrina Schreiner

Jens
Bosse

Manja
Czech-Sioli
&
Abel
Viejo-Borbolla




