FOR5200  DEEP-DV

Disrupt - Evade - Exploit

Gene expression and host response programming in DNA virus infection

Our Mission

The DFG-funded Research Unit FOR5200 DEEP-DV unites experts in molecular biology, virology, and bioinformatics to uncover how nuclear DNA viruses disrupt, evade or exploit host gene expression networks to pave the way for lytic, abortive, or persistent infection. Using state-of-the-art experimental and bioinformatic approaches, we compare virus–host interactions across major DNA virus families, including herpesviruses, adenoviruses, and polyomaviruses.

Video abspielen

P01
Melanie Brinkmann

P02
Lars
Dölken

P03 
Markus Landthaler

P04
Nicole
Fischer
P05
Adam Grundhoff

The single-cell DEEP-DV Transcription Atlas (Z01) captures viral and host gene expression over time during lytic infection.

 Z1

Caroline Friedel &
Florian Erhard

By applying standardized protocols as well as bioinformatic analysis across all projects, the DEEP-DV Atlas enables direct comparisons between viruses.

P07
Thomas Stamminger

P08
Sabrina Schreiner

P09
Jens
Bosse
P10
Manja
Czech-Sioli
&
Abel
Viejo-Borbolla

Video Section

Sprecherinnen

Prof. Dr. Melanie Brinkmann

Prof. Dr. Nicole Fischer

DEEP-DV in den sozialen Medien