FOR5200 DEEP-DV
Disrupt - Evade - Exploit
Gene expression and host response programming in DNA virus infection
Our Mission
The DFG-funded Research Unit FOR5200 DEEP-DV unites experts in molecular biology, virology, and bioinformatics to uncover how nuclear DNA viruses disrupt, evade or exploit host gene expression networks to pave the way for lytic, abortive, or persistent infection. Using state-of-the-art experimental and bioinformatic approaches, we compare virus–host interactions across major DNA virus families, including herpesviruses, adenoviruses, and polyomaviruses.



The single-cell DEEP-DV Transcription Atlas (Z01) captures viral and host gene expression over time during lytic infection.
Z1
Caroline Friedel &
Florian Erhard
By applying standardized protocols as well as bioinformatic analysis across all projects, the DEEP-DV Atlas enables direct comparisons between viruses.

P07
Thomas Stamminger

P08
Sabrina Schreiner

Jens
Bosse

Manja
Czech-Sioli
&
Abel
Viejo-Borbolla




