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3D rendering of a whole mount sample of an infected organoids

Human iPSC-derived organoids as infection model

Albertini et al bioRxiv 2025.02.10.637415; doi:https://doi.org/10.1101/2025.02.10.637415

Added value

 

Some infections, such as highly host-adapted viruses, cannot be studied in convetional cell culture or small animal models. Skin organoids are highly complex with many cell types and allow the study of bystander cell activation.